HPE-ProLiant DL388 Gen10
The HPE ProLiant DL388 Gen10 is a powerful 2U dual-socket rack server designed for enterprise computing, virtualization, databases, cloud infrastructure, and demanding data-center workloads. It combines Intel Xeon Scalable processors, high-capacity DDR4 ECC memory, flexible SAS/SATA/NVMe storage, HPE Smart Array RAID, extensive PCIe expansion, and HPE iLO 5 remote management in a scalable enterprise platform.
Description
The HPE ProLiant DL388 Gen10 is an enterprise-class 2U rack server engineered to provide a strong combination of computing performance, storage capacity, scalability, and reliability. It is suitable for organizations that need a versatile server platform capable of supporting demanding applications and evolving infrastructure requirements.
Powerful Intel Xeon Scalable Processing
The DL388 Gen10 supports Intel Xeon Scalable processors in a dual-socket architecture.
Depending on configuration, the server can be equipped with one or two Intel Xeon Bronze, Silver, Gold, or Platinum processors. This provides flexibility to optimize the server for different workloads, from general-purpose enterprise applications to highly parallelized databases, virtualization, analytics, and compute-intensive workloads.
Dual-processor configurations provide substantial core and thread capacity for server consolidation and demanding multi-user environments.
High-Capacity DDR4 ECC Memory
The DL388 Gen10 provides 24 DDR4 DIMM slots and supports ECC Registered DIMMs (RDIMM) and Load-Reduced DIMMs (LRDIMM).
Depending on processor and memory configuration, the platform supports up to 3TB of DDR4 memory.
High-capacity memory configurations are particularly useful for:
- Virtualization
- Databases
- In-memory applications
- Data analytics
- Enterprise applications
- Large-scale server consolidation
ECC memory provides error detection and correction capabilities to help maintain data integrity and system stability.
Flexible Storage
The DL388 Gen10 provides extensive storage flexibility, with configurations supporting SAS, SATA, SSD, and NVMe storage.
Depending on the selected chassis and backplane, the system can support different combinations of drive sizes and technologies.
Available configurations can include:
- 2.5-inch SFF drives
- 3.5-inch LFF drives
- SAS HDDs
- SATA HDDs
- SAS SSDs
- SATA SSDs
- NVMe SSDs
This flexibility allows the server to be configured either for high-capacity storage or high-performance applications.
HPE Smart Array RAID
The DL388 Gen10 supports HPE Smart Array controllers for enterprise storage management and RAID.
Depending on the installed controller, RAID levels can include:
- RAID 0
- RAID 1
- RAID 5
- RAID 6
- RAID 10
- RAID 50
- RAID 60
The exact RAID capabilities depend on the specific Smart Array controller and storage configuration.
High-Performance NVMe Storage
Selected configurations support NVMe SSDs, providing low-latency, high-throughput storage for demanding applications.
NVMe configurations are particularly beneficial for:
- Databases
- Virtualization
- High-transaction applications
- Analytics
- Enterprise application servers
- High-performance computing
The number of supported NVMe drives depends on the selected backplane and configuration.
Extensive PCIe Expansion
The DL388 Gen10 provides PCIe expansion capability for additional hardware such as:
- Network adapters
- Fibre Channel HBAs
- Storage controllers
- GPU accelerators
- High-speed connectivity adapters
- Specialized PCIe devices
This makes the platform adaptable to a wide range of enterprise and specialized workloads.
Advanced Networking
The server supports HPE networking technologies including FlexibleLOM and PCIe network adapters.
Depending on configuration, networking options can include:
- 1Gb Ethernet
- 10Gb Ethernet
- 25Gb Ethernet
- Fibre Channel adapters
- Other high-speed network interfaces
This allows the DL388 Gen10 to integrate into conventional enterprise networks, high-speed virtualization environments, and storage-area networks.
HPE iLO 5 Management
The DL388 Gen10 includes HPE Integrated Lights-Out 5 (iLO 5) for remote server management.
Administrators can use iLO to:
- Monitor server health
- Access a remote console
- Control system power
- Review hardware status
- Manage firmware
- Troubleshoot hardware
- Perform remote administration
This is particularly valuable for servers installed in remote or centralized data-center environments.
Enterprise Reliability
The DL388 Gen10 incorporates enterprise-oriented reliability features, including:
- ECC memory
- Hot-plug storage
- Redundant power options
- Hot-plug cooling fans
- HPE Smart Array RAID
- HPE iLO 5
- Redundant cooling
- Enterprise-class components
These features help minimize downtime and simplify maintenance in business-critical environments.
2U Rack-Mount Design
The 2U chassis provides additional room for storage, PCIe expansion, and cooling compared with a 1U server.
This makes the DL388 Gen10 a strong choice for organizations that require a combination of:
Compute performance + storage capacity + expansion capability
within a standard data-center rack.
Ideal Applications
The HPE ProLiant DL388 Gen10 is suitable for:
- Enterprise virtualization
- VMware environments
- Microsoft Hyper-V
- Database servers
- ERP and business applications
- Cloud infrastructure
- Private cloud
- Web and application hosting
- File servers
- Backup and disaster recovery
- Data analytics
- Server consolidation
- High-performance computing
- Enterprise storage
Key Specifications
| Feature | Specification |
|---|---|
| Product | HPE ProLiant DL388 Gen10 |
| Form Factor | 2U Rack Server |
| Processor | Intel Xeon Scalable |
| CPU Sockets | 2 |
| Memory | DDR4 ECC RDIMM / LRDIMM |
| DIMM Slots | 24 |
| Maximum Memory | Up to 3TB |
| Storage | SAS / SATA / SSD / NVMe options |
| Drive Form Factor | SFF / LFF, configuration dependent |
| RAID | HPE Smart Array |
| Networking | 1GbE / 10GbE / 25GbE and other options |
| Expansion | Multiple PCIe slots |
| Remote Management | HPE iLO 5 |
| Power | HPE Flex Slot hot-plug PSU options |
| Rack Height | 2U |
| Intended Use | Enterprise / Data Center |
Configuration Note
The HPE ProLiant DL388 Gen10 was offered in multiple configurations, so the exact Xeon processor, number of CPUs, RAM capacity, drive backplane, installed drives, RAID controller, network adapters, PCIe cards, power supplies, and operating system can vary.



