HPE-ProLiant DL380 Gen10
The HPE ProLiant DL380 Gen10 is a versatile 2U dual-socket rack server designed for enterprise applications, virtualization, databases, cloud infrastructure, and data-intensive workloads. Supporting Intel Xeon Scalable processors, up to 3TB of DDR4 memory, extensive SAS/SATA/NVMe storage options, HPE Smart Array RAID, and comprehensive iLO 5 management, it provides an excellent balance of performance, scalability, reliability, and expandability.
Description
The HPE ProLiant DL380 Gen10 is an enterprise-class 2U rack server designed to provide scalable computing, storage, and networking capabilities for demanding data-center environments. Its flexible architecture allows organizations to configure the server for virtualization, database applications, private cloud, enterprise applications, and high-capacity storage.
Powerful Intel Xeon Scalable Processing
The DL380 Gen10 features two Intel Xeon Scalable processor sockets, supporting a broad range of Intel Xeon Bronze, Silver, Gold, and Platinum processors.
Depending on configuration, users can install one or two processors and select from different core counts and clock speeds to match workload requirements.
Dual-socket operation provides substantial processing capacity for:
- Virtualization
- Databases
- Enterprise applications
- Cloud infrastructure
- Analytics
- High-performance computing
- Server consolidation
High-Capacity DDR4 Memory
The server provides 24 DDR4 DIMM slots, supporting Registered DIMMs (RDIMMs) and Load-Reduced DIMMs (LRDIMMs).
Depending on the selected processor and memory configuration, the DL380 Gen10 supports up to 3TB of DDR4 memory.
The high memory capacity makes the platform particularly suitable for virtualization hosts, large databases, in-memory applications, analytics, and other memory-intensive workloads.
Memory Features
- DDR4 ECC memory
- 24 DIMM slots
- RDIMM support
- LRDIMM support
- Large-capacity memory configurations
- Memory reliability and error correction
Flexible Storage Architecture
One of the major strengths of the DL380 Gen10 is its extensive storage flexibility.
Depending on the chassis and backplane configuration, the server can support combinations of:
- 2.5-inch SFF drives
- 3.5-inch LFF drives
- SAS HDDs
- SATA HDDs
- SAS SSDs
- SATA SSDs
- NVMe SSDs
The platform can be configured with a large number of drives, allowing organizations to optimize the server for either high-capacity storage or high-performance applications.
HPE Smart Array RAID
The DL380 Gen10 supports HPE Smart Array storage controllers for enterprise RAID and storage management.
Depending on the installed controller, supported RAID configurations can include:
- RAID 0
- RAID 1
- RAID 5
- RAID 6
- RAID 10
- RAID 50
- RAID 60
HPE Smart Array controllers provide hardware-assisted RAID functionality and are designed for enterprise storage environments.
NVMe and High-Performance Storage
Selected DL380 Gen10 configurations support NVMe SSDs, providing significantly higher storage performance and lower latency than conventional hard drives.
NVMe configurations are well suited to:
- Databases
- Virtualization
- High-transaction applications
- Analytics
- High-performance computing
- Application acceleration
The exact number of supported NVMe drives depends on the installed backplane and configuration.
Extensive Expansion Capability
The DL380 Gen10 provides numerous PCIe expansion possibilities.
Depending on the configuration, expansion slots can accommodate:
- Network adapters
- Fibre Channel HBAs
- Storage controllers
- GPU accelerators
- Graphics cards
- Additional PCIe devices
This makes the DL380 Gen10 highly adaptable to specialized enterprise requirements.
Advanced Networking
The server supports HPE FlexibleLOM and PCIe network adapters, allowing organizations to select networking speeds appropriate for their infrastructure.
Available options include:
- 1Gb Ethernet
- 10Gb Ethernet
- 25Gb Ethernet
- Fibre Channel
- High-speed network adapters
The flexible networking architecture makes the DL380 Gen10 suitable for conventional enterprise networks as well as high-speed virtualization and storage environments.
HPE iLO 5 Remote Management
The DL380 Gen10 includes HPE Integrated Lights-Out 5 (iLO 5) for remote server management.
iLO 5 allows administrators to remotely:
- Monitor server health
- Access the remote console
- Control server power
- Review hardware status
- Manage firmware
- Troubleshoot hardware
- Perform remote administration
This significantly simplifies server management in large data centers and geographically distributed environments.
Enterprise Reliability
The DL380 Gen10 incorporates enterprise-class reliability features, including:
- ECC memory
- Hot-plug drive support
- Redundant power supplies
- HPE Smart Array RAID
- HPE iLO 5
- Hot-plug cooling fans
- Redundant cooling
- Enterprise-grade components
Optional redundant hardware allows organizations to minimize downtime and maintain availability during component failures.
Flexible Power Supply Configuration
The server supports HPE Flex Slot hot-plug power supplies.
Depending on configuration, organizations can deploy redundant power supplies to improve system availability and provide additional power capacity for high-performance configurations.
2U Rack Design
The DL380 Gen10 uses a 2U rack-mounted chassis, providing a balance between computing power, storage capacity, and rack-space efficiency.
Its 2U form factor provides considerably more room for storage and expansion than a 1U server, making it particularly attractive for organizations requiring high storage density and extensive PCIe expansion.
Ideal Applications
The HPE ProLiant DL380 Gen10 is well suited for:
- Enterprise virtualization
- VMware environments
- Microsoft Hyper-V
- Database servers
- Cloud infrastructure
- Private cloud
- ERP and business applications
- Web and application hosting
- File servers
- Backup and disaster recovery
- Data analytics
- High-performance computing
- Enterprise storage
- Server consolidation
Key Specifications
| Feature | Specification |
|---|---|
| Product | HPE ProLiant DL380 Gen10 |
| Form Factor | 2U Rack Server |
| Processor | Intel Xeon Scalable |
| CPU Sockets | 2 |
| Memory | DDR4 ECC RDIMM / LRDIMM |
| DIMM Slots | 24 |
| Maximum Memory | Up to 3TB |
| Storage | SAS / SATA / SSD / NVMe options |
| Drive Form Factors | SFF / LFF, configuration dependent |
| RAID | HPE Smart Array |
| Networking | 1GbE / 10GbE / 25GbE and other options |
| Expansion | Multiple PCIe slots |
| Remote Management | HPE iLO 5 |
| Power | HPE Flex Slot hot-plug PSU |
| Rack Height | 2U |
| Intended Use | Enterprise / Data Center |
Configuration Note
The HPE ProLiant DL380 Gen10 was available in a very large number of configurations. Processor model, number of CPUs, RAM capacity, storage backplane, drive count and capacity, RAID controller, network adapters, GPU/accelerator, power supplies, and operating system can vary significantly.


